Marian Moldenhauer

Projects as a member

• CH20

  Stochasticity driving robust pattern formation in brain wiring

  Dr. Max von Kleist / Dr. Martin Weiser

  Project heads: Dr. Max von Kleist / Dr. Martin Weiser
  Project members: Marian Moldenhauer / Maureen Smith
  Duration: 01.06.2017 - 31.12.2019
  Status: running
  Located at: Freie Universität Berlin
  

  Description

  During brain development, synaptic connection patterns are formed in an extremely robust manner. As the interconnection patterns are much too complex to be encoded directly in the genome, they must emerge from simpler rules. In this project we investigate mechanistic stochastic models of axon growth and filopodial dynamics, checking whether their simulation leads to connection patterns and dynamics as observed in vivo, and with the same robustness.
  
  http://www.zib.de/projects/BrainWiring

• CH9

  Adaptive algorithms for optimization of hip implant positioning

  Dr. Martin Weiser / Dr.-Ing. Stefan Zachow

  Project heads: Dr. Martin Weiser / Dr.-Ing. Stefan Zachow
  Project members: Marian Moldenhauer
  Duration: -
  Status: completed
  Located at: Konrad-Zuse-Zentrum für Informationstechnik Berlin
  

  Description

  This project aims at a software environment supporting computer-assisted planning for total hip joint replacement by suggesting implant positions optimized for longevity of bone implants. The aim is to pre-operatively assess stress distribution in bone and to determine an optimal implant position with respect to natural function and stress distribution to prevent loosening, early migration, stress shielding, undesired bone remodeling, and fracture. Increasing the longevity of implants will help to enhance quality of life and reduce the cost of health care in aging societies. Focus of the research is the development of efficient optimization algorithms by adaptive quadrature of the high-dimensional space of daily motions and appropriate choice of tolerances for the underlying dynamic contact solver.
  
  http://www.zib.de/projects/adaptive-algorithms-optimization-hip-implant-positioning

Projects as a guest