Dr. Max von Kleist
Dr. Martin Weiser
Laufzeit: 01.06.2017 - 31.12.2019
Freie Universität Berlin
During brain development, synaptic connection patterns are formed in an extremely robust manner. As the interconnection patterns are much too complex to be encoded directly in the genome, they must emerge from simpler rules. In this project we investigate mechanistic stochastic models of axon growth and filopodial dynamics, checking whether their simulation leads to connection patterns and dynamics as observed in vivo, and with the same robustness.