Abstract: In recent years the mathematical modelling and simulation of biophysical and physiological processes have become powerful technologies that are used in different areas of basic research and applications. The talk focuses on such modelling and simulation in the context of liver diseases. The liver is a central metabolic organ in the human body that can suffer from various pathological conditions ranging from steatosis (fatty liver) to hepatocellular carcinoma and metastatic cancer. On the one hand blood flow and perfusion of the liver play an important role in the surgical and minimally invasive treatment of these pathologies. On the other hand blood flow and perfusion are central to the understanding of how the diseased liver works. The talk discusses mathematical modelling, simulation and optimisation for the surgical and minimally invasive treatment of liver cancer by predicting the outcome of the treatment, reducing the risks and increasing the success of the treatment. Moreover a multi-scale model and simulation of liver blood flow and metabolism is presented that help understanding the metabolic capacity of the diseased organ.
Mittwoch, 24. Juni 2015, 18 Uhr c.t.
Technische Universität Berlin
Institut für Mathematik,
Hörsaal MA 005
Straße des 17. Juni 136,